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LEUCINE-RICH REPEAT KINASE 2 (LRRK2) IBD

SPRINGER
08 / 2018
9783319842875
Inglés

Sinopsis

This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. Theácontributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The bookácovers the identification ofáLRRK2áas a major contributor to the pathogenesis of ParkinsonâÇÖs Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.

PVP
210,04